The Collapsin Response Mediator Protein 4 (CRMP4, DPYSL3, DRP-3, DRP3, ULIP, Dihydropyrimidinase-like 3) Antibody from MyBioSource.com is a Human, and Mouse Monoclonal antibody to CRMP4, DPYSL3, and TUC4. This antibody recognizes Human, Mouse, and Rat antigen. The Collapsin Response Mediator Protein 4 (CRMP4, DPYSL3, DRP-3, DRP3, ULIP, Dihydropyrimidinase-like 3) Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
DRP-3 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as a homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5. The unprocessed precursor is 570 amino acids long and has an estimated molecular weight of 61.9kD. It is mainly expressed in heart and skeletal muscle, but is also strongly expressed in fetal brain and spinal cord. It localizes to the cytoplasm and growth cone. This protein interacts with synaptic vesicle protein 2 and SH3A domain of intersectin